Lymphatic filariasis (LF) is an important public health problem endemic in 73 countries, where it is a major cause of acute and chronic morbidity and a significant impediment to socioeconomic development. It is targeted for elimination by 2020, through preventive chemotherapy using albendazole in combination with either ivermectin or diethylcarbamazine citrate. Preventive chemotherapy enables the regular and coordinated administration of safe, single-dose medications delivered through mass drug administration (MDA). Many countries are now scaling down MDA activities after achieving 100% geographic coverage and instituting monitoring and evaluation procedures to establish the impact of several consecutive rounds of MDA and determine if transmission has been interrupted. At the same time, countries yet to initiate MDA for elimination of LF will adopt improved mapping and coverage assessment protocols to accelerate the efforts for achieving global elimination by 2020. This review provides an update on treatment for LF and describes the current global status of the elimination efforts, transmission control processes and strategies for measuring impact and continuing surveillance after MDA has ceased.

译文

淋巴丝虫病(LF)是73个国家/地区的重要公共卫生问题,是急性和慢性发病的主要原因,也是社会经济发展的重大障碍。通过使用阿苯达唑与伊维菌素或柠檬酸二乙基卡巴嗪合用的预防性化学疗法,到2020年消除该病的目标。预防性化学疗法可以通过药物大规模管理(MDA)定期和协调地管理安全的单剂量药物。在实现100%的地理覆盖率并建立监视和评估程序以确定连续几轮MDA的影响并确定传输是否被中断之后,许多国家现在正在缩减MDA活动。同时,尚未启动消除LF的MDA的国家将采用改进的制图和覆盖率评估协议,以加速为在2020年之前实现全球消除而努力。这项审查提供了有关LF治疗的最新信息,并描述了LF的当前全球状况。在MDA停止后,采取消除措施,传输控制程序以及衡量影响和持续监视的策略。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录