This paper summarises the terrestrial ecotoxicity data submitted in the REACH registration dossiers and disseminated by ECHA. The analysis describes both the guidelines and the test species mostly used by registrants. REACH information requirements in relation to the effects on terrestrial organisms encompass three trophic levels; invertebrates, plants and micro-organisms, and the study of both long and short-term exposure. The results observed for soil invertebrates showed that on one hand there was a clear prevalence for testing on the species recommended by the standard test guidelines. On the other, the reporting included a large variety of species from very different families, demonstrating the feasibility for conducting toxicity tests on a number of relevant groups e.g. for species sensitivity distribution approaches. Standard toxicity testing with terrestrial plants under REACH follows a different approach and requires simultaneous testing on several species, using the same test conditions, adapted to each species, if needed. The test methods used to conduct the studies were only reported for 30% of cases. The most extensively reported test guidelines for terrestrial plants were OECD 208, ISO 11269-1 and ISO 11269-1. Information requirements for soil micro-organisms under REACH are related to the analysis of functional endpoints instead of on species or taxa. As recommended in REACH, OECD 216 and OECD 217 were the most often used test methods for soil micro-organisms. But overall, the test method was reported for only about 40% of the experimental studies. Moreover, it is noted that information on potential effects on soil micro-organisms is available for a limited number of REACH registered substances. The assessment suggests that providing waiving justifications and collecting available information, which in many cases might be well used for covering standard REACH data requirements, have been the main approaches used by registrants for the first REACH registration deadline.

译文

:本文总结了在REACH注册卷宗中提交并由ECHA传播的陆地生态毒性数据。分析同时描述了指南和主要由注册人使用的测试物种。与陆生生物影响有关的REACH信息要求包括三个营养级别。无脊椎动物,植物和微生物,以及长期和短期接触的研究。对土壤无脊椎动物观察到的结果表明,一方面,对标准测试指南建议的物种进行测试的流行率很明显。另一方面,该报告包括来自非常不同的科的多种物种,证明了对许多相关组进行毒性测试的可行性,例如:用于物种敏感性分布方法。在REACH下使用陆生植物进行标准毒性测试的方法有所不同,并且需要对几种物种同时进行测试,并使用相同的测试条件,并根据需要对每种物种进行调整。仅30%的病例报告了用于进行研究的测试方法。报道最广泛的陆地植物测试指南是OECD 208,ISO 11269-1和ISO 11269-1。根据REACH对土壤微生物的信息要求与功能性终点的分析有关,而不是物种或分类群的信息。根据REACH的建议,OECD 216和OECD 217是土壤微生物最常用的测试方法。但总体而言,只有40%的实验研究报告了该测试方法。此外,应注意的是,对于有限数量的REACH注册物质,可获得有关对土壤微生物的潜在影响的信息。评估表明,提供放弃的理由并收集可用的信息(在许多情况下可能很好地用于满足标准的REACH数据要求)已成为注册人在第一个REACH注册截止日期之前使用的主要方法。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录