BACKGROUND:Automated systems for the quantitative analysis of three-dimensional (3D) sets of intravascular ultrasound (IVUS) images have been developed to reduce the time required to perform volumetric analyses; however, 3D image reconstruction by these nongated systems is frequently hampered by cyclic artifacts.

METHODS AND RESULTS:We used an ECG-gated 3D IVUS image acquisition workstation and a dedicated pullback device in atherosclerotic coronary segments of 30 patients to evaluate (1) the feasibility of this approach of image acquisition, (2) the reproducibility of an automated contour detection algorithm in measuring lumen, external elastic membrane, and plaque+media cross-sectional areas (CSAs) and volumes and the cross-sectional and volumetric plaque+media burden, and (3) the agreement between the automated area measurements and the results of manual tracing. The gated image acquisition took 3.9+/-1.5 minutes. The length of the segments analyzed was 9.6 to 40.0 mm, with 2.3+/-1.5 side branches per segment. The minimum lumen CSA measured 6.4+/-1.7 mm2, and the maximum and average CSA plaque+media burden measured 60.5+/-10.2% and 46.5+/-9.9%, respectively. The automated contour-detection required 34.3+/-7.3 minutes per segment. The differences between these measurements and manual tracing did not exceed 1.6% (SD<6.8%). Intraobserver and interobserver differences in area measurements (n=3421; r=.97 to.99) were <1.6% (SD<7.2%); intraobserver and interobserver differences in volumetric measurements (n=30; r=.99) were <0.4% (SD<3.2%).

CONCLUSIONS:ECG-gated acquisition of 3D IVUS image sets is feasible and permits the application of automated contour detection to provide reproducible measurements of the lumen and atherosclerotic plaque CSA and volume in a relatively short analysis time.

译文

背景:已开发出用于对三维(3D)血管内超声(IVUS)图像进行定量分析的自动化系统,以减少执行体积分析所需的时间;但是,这些非门控系统进行的3D图像重建经常会受到循环伪像的干扰。评估30位患者的动脉粥样硬化性冠状动脉节段(1)这种图像采集方法的可行性,(2)自动轮廓检测算法在测量管腔,外部弹性膜和斑块介质横截面积(CSA)时的可重复性,以及体积,横截面和体积斑块介质负荷,以及(3)自动化面积测量与手动追踪结果之间的一致性。门控图像采集耗时3.9 /-1.5分钟。分析的片段的长度为9.6至40.0mm,每个片段具有2.3 / -1.5个侧分支。最小内腔CSA的大小为6.4 /-1.7 mm2,最大和平均CSA斑块的介质负荷分别为60.5 /-10.2%和46.5 /-9.9%。自动轮廓检测每段需要34.3 /-7.3分钟。这些测量值和手动跟踪之间的差异不超过1.6%(SD <6.8%)。观察者之间和观察者之间的面积测量差异(n = 3421; r ​​= .97至0.99)<1.6%(SD <7.2%);观察者内部和观察者之间的体积测量差异(n = 30; r = .99)<0.4%(SD <3.2%)。

结论:ECG门控采集3D IVUS图像集是可行的,并允许应用自动轮廓检测,以在相对较短的分析时间内对管腔和动脉粥样硬化斑块CSA和体积进行可重复的测量。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录