A method for quantifying the fluctuations of the QRS electrocardiogram over the flat (unrolled) thoracic surface in normal subjects is presented. Serial comparisons were performed on 32-lead ECG recordings and body surface maps from seven healthy men, using as similarity measures correlation and RMS-difference in both time-signal and 2D map domain. Recordings were made on one and the same day, and on different days. The time-signal correlation and RMS-differences were plotted as 2D distributions. Correlation was higher on the front of the torso and RMS-differences were largest in the precordial area. The average time-signal correlation calculated over the QRS in comparisons of signals taken on different days was 0.9717, whereas the corresponding RMS-difference was 57.8 microV. Additionally, 2D comparisons between reconstructed map frames at different time instants in the QRS were carried out, using the 2D versions of the correlation and RMS-difference. The averaged results of the 2D comparisons were close to the time-signal comparison values (respectively 0.9696 and 68.9 microV). Finally, 2D comparisons between isointegral maps (mapping the QRS signal integral) were performed. They yielded even higher correlations (0.98, 3.453 microV s). Although the number of subjects studied was not large, the investigation brought to light important variability ranges that may serve as a basis when detecting pathologies. In addition, the topology of normal ECG variability on the body surface was revealed. This study confirmed the pertinence of correlation and RMS-difference as measures of time-signal and map similarity.

译文

提出了一种在正常受试者中平坦(展开)的胸廓表面上QRS心电图波动的量化方法。对来自七个健康男性的32导联心电图记录和身体表面图进行系列比较,使用相似性度量在时间信号和二维图域中的相关性和均方根差。记录是在同一天,同一天和不同日期进行的。将时间信号相关性和RMS差绘制为2D分布。躯干前部的相关性较高,并且前胸区的RMS差异最大。通过QRS计算出的不同时间的信号比较中的平均时间信号相关性为0.9717,而相应的RMS差为57.8 microV。此外,使用相关性和RMS差异的2D版本,在QRS中不同时刻重建的地图帧之间进行了2D比较。二维比较的平均结果接近时间信号比较值(分别为0.9696和68.9 microV)。最后,进行了等积分图之间的二维比较(映射QRS信号积分)。他们产生了更高的相关性(0.98,3.453 microV s)。尽管研究的对象数量并不多,但这项研究揭示了重要的可变性范围,可以作为检测病理的基础。另外,揭示了正常ECG在体表上的变异性的拓扑结构。这项研究证实了相关性和RMS差作为时间信号和地图相似性的度量的相关性。

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