BACKGROUND:Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D). The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabetic children and adolescents. METHODS:The study included 202 children and adolescents with T1D. Demographic data and laboratory findings were obtained from patients files. RESULTS:Dyslipidemia prevalence was found to be 26.2%. Hypercholesterolemia (15.8%) and hyperglyceridemia (12.9%) were most common findings. Age, body mass index (BMI), hemoglobin A1c (A1C) and poor metabolic control were significantly higher in cases with dyslipidemia. Smoking rate was 14.1% in the pubertal group. Poor metabolic control and dyslipidemia was found higher among smokers (p<0.05). CONCLUSIONS:Blood lipid levels should be monitored regularly and nutrition education should be repeated periodically to prevent and control dyslipidemia in patients with T1D. Smoking-related risks should be a part of patient education in the pubertal period.

译文

背景:血脂异常会增加1型糖尿病(T1D)的微血管和大血管并发症的发生频率和严重程度。本研究旨在确定血脂异常的患病率及其与糖尿病儿童和青少年的临床和实验室检查结果的关系。
方法:该研究包括202名患有T1D的儿童和青少年。人口统计学数据和实验室检查结果来自患者档案。
结果:血脂异常患病率为26.2%。高胆固醇血症(15.8%)和高甘油血症(12.9%)是最常见的发现。血脂异常患者的年龄,体重指数(BMI),血红蛋白A1c(A1C)和不良的代谢控制均明显更高。青春期组吸烟率为14.1%。在吸烟者中,不良的代谢控制和血脂异常被发现较高(p <0.05)。
结论:应定期监测血脂水平,并定期重复营养教育,以预防和控制T1D患者的血脂异常。在青春期,与吸烟有关的风险应作为患者教育的一部分。

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