OBJECTIVES:To assess the reliability of diffusion tensor imaging (DTI)-based fibre tractography (FT), which is a prerequisite for clinical applications of this technique. Here we assess the test-retest reproducibility of the architectural and microstructural features of two clinically relevant tracts reconstructed with DTI-FT. METHODS:The corticospinal tract (CST), arcuate fasciculus (AF) and its long segment (AFl) were reconstructed in 17 healthy subjects imaged twice using a deterministic approach. Coefficients of variation (CVs) of diffusion-derived tract values were used to assess the microstructural reproducibility. Spatial correlation and fibre overlap were used to assess the architectural reproducibility. RESULTS:Spatial correlation was 68 % for the CST and AF, and 69 % for the AFl. Overlap was 69 % for the CST, 61 % for the AF, and 59 % for the AFl. This was comparable to 2-mm tract shift variability. CVs of diffusion-derived tract values were at most 3.4 %. CONCLUSIONS:The results showed low architectural and microstructural variability for the reconstruction of the tracts. The architectural reproducibility results encourage the further investigation of the use of DTI-FT for neurosurgical planning. The high microstructural reproducibility results are promising for using DTI-FT in neurology to assess or predict functional recovery.

译文

目的:评估基于弥散张量成像(DTI)的纤维束成像(FT)的可靠性,这是该技术临床应用的先决条件。在这里,我们评估了用DTI-FT重建的两个临床相关道的结构和微结构特征的重测重现性。
方法:采用确定性方法,对17例健康受试者进行了两次成像,分别重建了皮质脊髓束(CST),弓形筋膜(AF)及其长节(AF1)。扩散衍生管道值的变异系数(CV)用于评估微观结构的可重复性。空间相关性和纤维重叠被用来评估建筑的可重复性。
结果:CST和AF的空间相关性为68%,AF1的空间相关性为69%。 CST的重叠率为69%,AF的重叠为61%,AF1的重叠为59%。这相当于2毫米的道偏移变化。扩散源的CV值最多为3.4%。
结论:结果表明,重建道的建筑和微观结构变异性较低。结构的可重复性结果鼓励进一步研究DTI-FT在神经外科计划中的应用。在神经病学中使用DTI-FT评估或预测功能恢复具有很高的微结构可再现性结果。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录