Lymphogranuloma venereum (LGV) cases are currently re-emerging in the homosexual community, particularly in HIV-seropositive patients. The standard treatment for this infection, which is caused by Chlamydia trachomatis L1, L2 and L3 serotypes, is a 3-week doxycycline regimen. The case is reported of a male patient presenting with LGV, who was rapidly cured with moxifloxacin treatment after failure of extended treatment with cyclines. This fluoroquinolone is known to be highly active in vitro on the LGV pathogenic agent. Thus it may be a useful alternative when doxycycline treatment results in failure.

译文

:同性恋性淋巴肉芽肿(LGV)病例目前正在重新出现,尤其是在HIV血清阳性患者中。由沙眼衣原体L1,L2和L3血清型引起的这种感染的标准治疗是3周的强力霉素方案。该病例报道了一名男性患者,患有LGV,在用环素进行长期治疗失败后迅速用莫西沙星治愈。已知该氟喹诺酮在体外对LGV病原体具有高活性。因此,当强力霉素治疗导致失败时,它可能是一个有用的替代方法。

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