Early detection and staging of lung cancer is important in initiating rapid treatment and improving prognosis. Computed tomography (CT) and magnetic resonance (MR) imaging have a high resolution and are able to reveal structural abnormalities, but still have problems differentiating benign from malignant lesions. Lesion size is used as a distinguishing parameter but definite diagnosis still relies on invasive procedures. Positron emission tomography (PET) is based on imaging of biochemical processes in vivo. PET is unique by disclosing metabolic differences between benign and malignant disease, e.g. glucose utilization. Here, the role of PET in diagnosis and (re)-staging of lung cancer as well as monitoring of therapy response will be reviewed.

译文

肺癌的早期发现和分期对于开始快速治疗和改善预后至关重要。计算机断层扫描 (CT) 和磁共振 (MR) 成像具有高分辨率,能够揭示结构异常,但在区分良性和恶性病变方面仍然存在问题。病变大小用作区分参数,但明确的诊断仍依赖于侵入性操作。正电子发射断层扫描 (PET) 基于体内生化过程的成像。PET通过揭示良性和恶性疾病 (例如葡萄糖利用) 之间的代谢差异而独特。在这里,将回顾PET在肺癌的诊断和 (再) 分期以及监测治疗反应中的作用。

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