A series of experiments addressed the issue of comparability among neurological processes in pigmented rat and human visual systems. In the first set of experiments, transient visual-evoked potentials (VEPs) were elicited by the onset of sine-wave gratings of various spatial frequencies. The spatial frequency-response profiles of the first positive and immediately succeeding negative components differed from one another, but were similar in the two species. In addition, amplitude of the negative, but not the positive, component was strongly attenuated in both species following stationary pattern adaptation. In the second set of experiments, steady-state VEPs were elicited by the onset and offset of the gratings. The spatial frequency profiles of the 1F (response amplitude at the frequency of stimulus onset-offset) and 2F response components differed from one another, but were similar in both species. The final set of experiments indicated that diazepam, a GABA agonist, reduced amplitude of 2F, but not 1F, in both species. These results suggested that at least some functional subsystems mediating spatial vision in humans may have qualitatively similar counterparts in rats.

译文

一系列实验解决了有色大鼠和人类视觉系统中神经过程之间的可比性问题。在第一组实验中,通过各种空间频率的正弦波光栅的出现引起了瞬态视觉诱发电位 (vep)。第一个正分量和紧随其后的负分量的空间频率响应曲线彼此不同,但在两个物种中相似。此外,在固定模式适应之后,两个物种的负成分 (而非正成分) 的振幅都强烈减弱。在第二组实验中,稳态vep是由光栅的开始和偏移引起的。1F (刺激开始偏移频率下的响应幅度) 和2F响应分量的空间频率分布彼此不同,但两种物种相似。最后一组实验表明,地西epa (一种GABA激动剂) 在两种物种中均降低了2F的振幅,但没有降低1F的振幅。这些结果表明,至少一些介导人类空间视觉的功能子系统在大鼠中可能具有定性相似的对应物。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录