The clinical literature increasingly indicates that cardiovascular risk factors and cardiovascular disease (CVD) are more common among individuals with posttraumatic stress disorder (PTSD). Depression also poses a risk for CVD and is often comorbid with PTSD. Research to date has not established whether PTSD is associated with additional CVD risk beyond the risks associated with comorbid depression. The authors examined relationships of lifetime PTSD and depression with high blood pressure in data from the US National Comorbidity Survey. They divided participants into 4 mutually exclusive diagnostic groups: (1) PTSD history and no depression history, (2) PTSD and depression history, (3) depression history and no PTSD history, and (4) no history of mental disorder. Hypertension prevalence was higher for the PTSD, no depression and PTSD plus depression groups compared with the depression only and no mental disorder groups. PTSD appears to be related to hypertension independent of depression. This may partially explain elevated rates of CVD in PTSD patients.

译文

临床文献越来越多地表明,心血管危险因素和心血管疾病 (CVD) 在创伤后应激障碍 (PTSD) 患者中更为常见。抑郁症也有心血管疾病的风险,通常与创伤后应激障碍并存。迄今为止的研究尚未确定PTSD是否与除与合并症抑郁症相关的风险之外的其他CVD风险相关。作者在美国国家合并症调查的数据中研究了终生PTSD和抑郁症与高血压的关系。他们将参与者分为4个互斥的诊断组 :( 1) PTSD病史和无抑郁史,(2) PTSD和抑郁史,(3) 抑郁史和无PTSD病史,以及 (4) 无精神障碍史。PTSD,无抑郁和PTSD加抑郁组的高血压患病率高于仅抑郁组和无精神障碍组。PTSD似乎与高血压有关,而与抑郁症无关。这可能部分解释了PTSD患者CVD发生率的升高。

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