The emergence of severe acute respiratory syndrome (SARS) underscored the importance of influenza detection and response in China. From 2004, the Chinese National Influenza Center (CNIC) and the United States Centers for Disease Control and Prevention (USCDC) initiated Cooperative Agreements to build capacity in influenza surveillance in China.From 2004 to 2014, CNIC and USCDC collaborated on the following activities: 1) developing human technical expertise in virology and epidemiology in China; 2) developing a comprehensive influenza surveillance system by enhancing influenza-like illness (ILI) reporting and virological characterization; 3) strengthening analysis, utilization and dissemination of surveillance data; and 4) improving early response to influenza viruses with pandemic potential.Since 2004, CNIC expanded its national influenza surveillance and response system which, as of 2014, included 408 laboratories and 554 sentinel hospitals. With support from USCDC, more than 2500 public health staff from China received virology and epidemiology training, enabling > 98% network laboratories to establish virus isolation and/or nucleic acid detection techniques. CNIC established viral drug resistance surveillance and platforms for gene sequencing, reverse genetics, serologic detection, and vaccine strains development. CNIC also built a bioinformatics platform to strengthen data analysis and utilization, publishing weekly on-line influenza surveillance reports in English and Chinese. The surveillance system collects 200,000-400,000 specimens and tests more than 20,000 influenza viruses annually, which provides valuable information for World Health Organization (WHO) influenza vaccine strain recommendations. In 2010, CNIC became the sixth WHO Collaborating Centre for Influenza. CNIC has strengthened virus and data sharing, and has provided training and reagents for other countries to improve global capacity for influenza control and prevention.The collaboration's successes were built upon shared mission and values, emphasis on long-term capacity development and sustainability, and leadership commitment.

译文

严重急性呼吸系统综合症 (传染性非典型肺炎) 的出现凸显了中国流感检测和应对的重要性。从2004年起,中国国家流感中心 (CNIC) 和美国疾病控制与预防中心 (USCDC) 启动了合作协议,以建设中国的流感监测能力。从2004 2014年开始,CNIC和USCDC合作开展了以下活动: 1) 在中国发展人类在病毒学和流行病学方面的技术专长; 2) 通过加强流感样疾病 (ILI) 报告和病毒学表征来开发全面的流感监测系统; 3) 加强监测数据的分析,利用和传播; 和4) 改善对流感病毒的早期反应。自2004年以来,CNIC扩大了其国家流感监测和应对系统,2014年包括408个实验室和554个哨点医院。在美国疾病预防控制中心的支持下,来自中国的2500多名公共卫生人员接受了病毒学和流行病学学培训,使>   98% 个网络实验室能够建立病毒分离和/或核酸检测技术。CNIC建立了病毒耐药性监测和基因测序,反向遗传学,血清学检测和疫苗株开发平台。CNIC还建立了一个生物信息学平台,以加强数据分析和利用,每周发布中英文在线流感监测报告。该监测系统每年收集200,000-400,000份标本并检测超过20,000种流感病毒,为世卫组织流感疫苗株推荐提供了有价值的信息。2010年,CNIC成为世卫组织第六个流感合作中心。CNIC加强了病毒和数据共享,并为其他国家提供了培训和试剂,以提高全球控制和预防流感的能力。合作的成功建立在共同的使命和价值观,强调长期能力发展和可持续性以及领导承诺的基础上。

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