The feasibility of using a subcutaneously implanted portal system attached to a conventional 16-gauge epidural catheter has been evaluated in 50 patients with sever pain associated with cancer. This technique allowed for the percutaneous epidural administration of morphine at 8-12-hourly intervals for pain control. The mean duration of implantation was 12 weeks and the longest period a portal remained in situ was 36 weeks. Five portals had to be removed for various reasons. The injection system has blocked on eight occasions due to catheter blockage (six times) and portal blockage (two occasions). These patients have continued to obtain excellent analgesia when either catheter or portal were replaced. In a cadaver, 300 injections were simulated using either 22-gauge Huber point needles or disposable needles (25 gauge) and the injectate examined by both light and scanning electron microscopy. Both needle types resulted in particulate contamination which was greater with the recommended Huber point needles.

译文

已在50例与癌症相关的严重疼痛患者中评估了使用固定在常规16号硬膜外导管上的皮下植入门静脉系统的可行性。该技术允许以8-12小时的间隔经皮硬膜外施用吗啡以控制疼痛。植入的平均持续时间为12周,而原位保留的最长时间为36周。由于各种原因,必须删除五个门户。由于导管阻塞 (六次) 和门静脉阻塞 (两次),注射系统有八次阻塞。当更换导管或门静脉时,这些患者继续获得出色的镇痛效果。在尸体中,使用22号Huber点针或一次性针 (25号) 模拟300注射,并通过光学和扫描电子显微镜检查注射物。两种类型的针头都会导致颗粒污染,推荐的Huber点针头会更大。

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