Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening, adverse effect of heparin therapy. Patients with this complication require an alternative approach to anticoagulation. Bivalirudin is a direct thrombin inhibitor with an efficacy comparable to that of heparin, a short half-life, and reduced bleeding complications in adults. We present the case of a 2-year-old boy with HIT Type II who underwent recanalization of an occluded superior vena cava and stent placement, utilizing bivalirudin as anticoagulant.

译文

肝素诱导的血小板减少症 (HIT) 是肝素治疗的潜在威胁生命的不良反应。患有这种并发症的患者需要另一种抗凝方法。比伐卢定是一种直接凝血酶抑制剂,其疗效与肝素相当,半衰期短,并减少了成人的出血并发症。我们介绍了一个2岁的II型HIT男孩的病例,该男孩利用比伐卢定作为抗凝剂进行了闭塞的上腔静脉再通和支架置入。

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