Noradrenaline (NA) is the active component of novel antifouling agents and acts by preventing attachment of fouling organisms. The goal of this study was to examine the toxicity of NA to the non-target zooplankton D. magna and C. dubia. Neonates were exposed to one of five concentrations of NA and effects on survival, reproduction and molting were determined. Calculated LC50 values were determined to be 46 and 38 μM in C. dubia and D. magna, respectively. A 10-day C. dubia study found that reproduction metrics were significantly impacted at non-lethal concentrations. In D. magna, concentrations greater than 40 μM significantly impacted molting. A toxicity test was conducted with D. magna using oxidized NA, which yielded similar results. These data indicate that both NA and oxidized NA are toxic to non-target zooplankton. Results obtained from this study can be used to guide future ecological risk assessments of catecholamine-based antifouling agents.

译文

去甲肾上腺素 (NA) 是新型防污剂的活性成分,通过防止结垢生物的附着而起作用。这项研究的目的是检查NA对非目标浮游动物D. magna和C. dubia的毒性。新生儿暴露于五种浓度的NA之一,并确定了对存活,繁殖和蜕皮的影响。在C. dubia和D. magna中,计算出的LC50值分别确定为46和38μm。一项为期10天的C. dubia研究发现,在非致命浓度下,生殖指标会受到显着影响。在D. magna中,浓度大于40μm会显着影响蜕皮。使用氧化NA对D. magna进行了毒性试验,结果相似。这些数据表明NA和氧化NA对非目标浮游动物都是有毒的。从这项研究中获得的结果可用于指导基于儿茶酚胺的防污剂的未来生态风险评估。

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