Bi-hemispheric cerebral blood flow (CBF) measurements during rest and hyperventilation, with intra-arterial 133Xe injection method, were investigated in 19 cases, angiographically diagnosed as unilateral internal carotid artery (ICA) occlusion, including 8 cases with TIAs and 11 cases with completed strokes as the onset. Indices of cerebral vascular resistance and CO2 reactivity with decreasing arterial PCO2 were also investigated. A significant decrease (P less than 0.05) of hemispheric mean CBF was noted in the ischemic hemisphere, but normal flow values in the unaffected hemisphere and preserved CO2 responsiveness during hyperventilation were observed in both the affected and unaffected hemispheres in patients with TIAs. Moreover, a direct relationship between CBF and blood pressure, observed in 11 cases with completed strokes, was not recognized in 8 cases with TIAs. A degree of the abnormalities of the affected hemisphere in cerebral circulation was suggested to be somewhat different between TIAs and completed strokes in ICA occlusions, and bi-hemispheric CBF measurements would be an useful method for evaluating the various indices of the CBF in ICA occlusions.

译文

在19例经血管造影诊断为单侧颈内动脉(ICA)阻塞的病例中,调查了19例经静息和过度通气期间双半球脑血流量(CBF)的测量,包括8例TIA和11例完成中风为发作。还研究了脑血管阻力和CO2反应性随动脉PCO2降低的指标。在缺血半球中,半球平均CBF显着降低(P小于0.05),但是在TIA患者的受影响和未受影响的半球中,未受影响的半球中的正常血流值和过度换气过程中观察到的CO2响应保持不变。此外,在11例完成卒中的患者中,未发现CBF与血压之间的直接关系,在8例TIA患者中未发现。提示TIA与ICA闭塞中的完整卒中在大脑循环中受影响的半球的异常程度有所不同,双半球CBF测量将是评估ICA闭塞中CBF各项指标的有用方法。

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