The in vitro activity of 21 antimicrobial agents against 143 Acinetobacter strains (belonging to 12 different DNA hybridization groups) was studied. Of the antibiotics tested, ciprofloxacin, ofloxacin, doxycycline and imipenem had the lowest MICs. For most antibiotics there was a considerable overlap of the MICs between the DNA groups; however, some differences in antimicrobial susceptibility between DNA groups were found. Strains of DNA groups 2 (A. baumannii) and 13 (unnamed) were most resistant, and strains of DNA groups 8 (A. lwoffii) and 5 (A. junii) less resistant. Many DNA groups contain both saccharolytic and non-saccharolytic strains but in the present study no differences in antimicrobial susceptibility were found between strains of a particular DNA group with regard to this property.

译文

研究了21种抗菌剂对143不动杆菌菌株 (属于12个不同的DNA杂交组) 的体外活性。在测试的抗生素中,环丙沙星,氧氟沙星,强力霉素和亚胺培南的mic最低。对于大多数抗生素,DNA组之间的mic有相当大的重叠; 但是,发现DNA组之间的抗菌药物敏感性存在一些差异。DNA组2 (鲍曼不动杆菌) 和13 (未命名) 的菌株抗性最高,而DNA组8 (A. lwoffii) 和5 (A. junii) 的菌株抗性较低。许多DNA组同时包含糖分解和非糖分解菌株,但在本研究中,就该特性而言,特定DNA组的菌株之间未发现抗菌药物敏感性差异。

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