BACKGROUND:The aim of the present research was to evaluate the relationship between Mediterranean dietary quality index (Med-DQI) and dietary phytochemical index (DPI) with metabolic risk factors of cardiovascular disease in candidates for coronary artery bypass graft (CABG) surgery. METHODS:This was a cross-sectional study on 454 patients aged 35-80 years as candidates of CABG and hospitalized in Tehran Heart Center. Anthropometric and demographic characteristics were obtained from all participants and a 138-item semi-quantitative food frequency questionnaire (FFQ) was used to evaluate Med-DQI and DPI. Biochemical parameters including HbA1C, serum lipids, albumin, creatinine and C-reactive protein (CRP) were assessed by commercial laboratory methods. RESULTS:Patients with higher scores of "saturated fatty acids" had lower serum albumin concentrations (P < 0.05). High scores of "cholesterol" subgroup was also accompanied with higher serum Hb A1C percent (P = 0.04). Significantly higher concentrations of serum creatinine were also observed in categorizes with lower "fish" scores. Patients with lower phytochemical intakes had significantly higher Med-DQI scores. CONCLUSION:According to our findings, high dietary intakes of saturated fatty acids and cholesterol were associated with low serum albumin and Hb A1C concentration. Further studies are needed to better clarify these associations and possible underlying mechanisms.

译文

背景:本研究的目的是评估冠状动脉搭桥术(CABG)候选者的地中海饮食质量指数(Med-DQI)和饮食植物化学指数(DPI)与心血管疾病的代谢危险因素之间的关系。
方法:这是一项横断面研究,对454位35-80岁的CABG候选人并在德黑兰心脏中心住院的患者进行了研究。从所有参与者获得人体测量学和人口统计学特征,并使用138个项目的半定量食物频率问卷(FFQ)来评估Med-DQI和DPI。通过商业实验室方法评估了包括HbA1C,血脂,白蛋白,肌酐和C反应蛋白(CRP)在内的生化参数。
结果:“饱和脂肪酸”得分较高的患者血清白蛋白浓度较低(P <0.05)。高分的“胆固醇”亚组还伴有更高的血清Hb A1C百分比(P = 0.04)。在“鱼”得分较低的类别中也观察到明显较高的血清肌酐浓度。植物化学摄入量较低的患者的Med-DQI评分显着较高。
结论:根据我们的发现,高饮食中饱和脂肪酸和胆固醇的摄入与低血清白蛋白和Hb A1C浓度有关。需要进一步研究以更好地阐明这些关联和可能的潜在机制。

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