Feeding vessel sign is very sensitive radiological finding of septic pulmonary embolism. In the appropriate clinical context, if the CT scan of a patient with suspected sepsis shows this radiological sign, empirical antibiotics (including gram positive organisms) should be started at the earliest after sending all cultures to decrease mortality and morbidity. Here we are presenting a case of 14-years-old boy with left ankle septic arthritis and septic pulmonary embolism.