Corticosteroids, while providing rapid remission and ongoing control of symptoms of autoimmune blistering diseases (AIBD), have numerous potentially serious acute and long-term side effects. Evidence-based medicine has reevaluated the various types of corticosteroids and forms of corticosteroid delivery in AIBD to ascertain whether any advantages of specific delivery systems or regimens exist. Careful monitoring of patients and simple preventive measures are effective in minimizing the adverse outcomes associated with their use. This article outlines the current level of evidence for corticosteroid use in AIBDs, and discusses appropriate investigations and interventions to minimize or prevent the associated adverse effects.

译文

:皮质类固醇可提供快速缓解并持续控制自身免疫性水疱病(AIBD)症状,但具有许多潜在的严重急性和长期副作用。循证医学已经重新评估了AIBD中各种类型的皮质类固醇和皮质类固醇的递送形式,以确定特定的递送系统或治疗方案是否存在任何优势。仔细监视患者并采取简单的预防措施可有效减少与使用相关的不良后果。本文概述了AIBD中使用皮质类固醇的现有证据水平,并讨论了适当的调查和干预措施,以最大程度地减少或预防相关的不良影响。

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