A prospective collection of positive antimicrobial cultures was performed over 12 consecutive months in the medical intensive care unit of a cancer hospital. In all, 144 infections and 163 pathogens were documented during 87 of the 528 admissions. Lung, urinary, ENT (ear, nose and throat) infections and bacteraemia were the most frequently documented. Staphylococcus species, Streptococcus species, Escherichia coli, Klebsiella species and Pseudomonas species were the most common pathogens. Gram-positive strains were observed predominantly during monomicrobial bacteraemia (48.9%). Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis (MRSE) were found in 58% and 92% of the isolated strains respectively. No particular outbreak was identified. A further prospective study will be necessary to evaluate the impact of the antibiotic use on the selection of resistant strains in our ICU.

译文

:在癌症医院的医疗重症监护室连续12个月进行了前瞻性抗菌药物阳性培养。在528例入院病例中,总共记录了144例感染和163种病原体。肺,尿,耳鼻喉(耳,鼻,喉)感染和菌血症的记录最频繁。葡萄球菌,链球菌,大肠杆菌,克雷伯菌和假单胞菌是最常见的病原体。革兰氏阳性菌株主要在单微生物菌血症期间观察到(48.9%)。分别在58%和92%的分离菌株中发现了耐甲氧西林的金黄色葡萄球菌(MRSA)和表皮葡萄球菌(MRSE)。没有发现特定的爆发。有必要进行进一步的前瞻性研究,以评估抗生素使用对我们ICU中耐药菌株选择的影响。

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