Various strategies using a ventricular assist device (VAD) are applied to rescue Interagency Registry for Mechanically Assisted Circulatory Support profile 1 (Profile-1) patients. However, the optimal use of VAD in Profile-1 patients has not been completely elucidated. We retrospectively reviewed 23 Profile-1 patients [mean age 36.9 ± 16.6 years, 14 males; 11 with non-ischemic cardiomyopathy (NICM), 9 with fulminant myocarditis (FM), 2 with ischemic cardiomyopathy (ICM), and 1 with peripartum cardiomyopathy (PPCM); 18 with pre-operative percutaneous extracorporeal membrane oxygenation (p-ECMO) support] who underwent VAD implantation from 2011 to 2015 at our institution. Nine initially received left VAD (LVAD) alone (NICM in 9, ICM in 2 with ICM, and FM in 1), one with NICM received biventricular VAD (BiVAD; n = 1), and 10 received LVAD combined with right ventricular support using an ECMO circuit (BiVAD-ECMO) (FM in 8, NICM in 1, and PPCM in 1). Paracorporeal VAD was used in all patients. ECMO was used for the patients with severe pulmonary edema, inflammation, anemia, and thrombopenia. The BiVAD patient died 1.4 months after VAD implantation. The overall survival was comparable between patients with BiVAD-ECMO and LVAD (2-year survival, 80.0 and 75.0%, respectively). Three VAD strategies were initially applied in Profile-1 patients. Among them, the BiVAD-ECMO strategy is a promising therapeutic option to rescue Profile-1 patients with multiple organ failure.

译文

:使用心室辅助设备(VAD)的各种策略可用于挽救机械辅助循环支持配置文件1(Profile-1)患者的机构间注册表。但是,尚未完全阐明Profile-1患者中VAD的最佳用法。我们回顾性地回顾了23例Profile-1患者[平均年龄36.9±16.6岁,14例男性;非缺血性心肌病(NICM)11例,暴发性心肌炎(FM)9例,缺血性心肌病(ICM)2例,围产期心肌病(PPCM)1例; 18例术前经皮体外膜氧合作用(p-ECMO)支持,他们于2011年至2015年在我们机构接受了VAD植入。最初有9个单独接受左VAD(LVAD)(NICM为9个,ICM为2个,ICM为FM,1个为FM),一个NICM则接受双心室VAD(BiVAD; n = 1),另外10个接受LVAD联合右心室支持ECMO电路(BiVAD-ECMO)(FM输入为8,NICM输入为1,PPCM输入为1)。所有患者均使用了体外VAD。 ECMO用于严重肺水肿,炎症,贫血和血小板减少症的患者。 BiVAD患者在VAD植入后1.4个月死亡。 BiVAD-ECMO和LVAD患者的总体生存率相当(2年生存率分别为80.0和75.0%)。最初在Profile-1患者中应用了三种VAD策略。其中,BiVAD-ECMO策略是挽救多器官功能衰竭的Profile-1患者的有前途的治疗选择。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录