Propolis is a glue, prepared by honeybees from plant materials to stick their hives on the beehive wall. It has gained popularity in Japan as a healthy drink and people believe that propolis can cure inflammation, heart diseases and even diabetes and cancer. We have evaluated the β-cell protective effect of propolis against the toxicity of streptozotocin (STZ) in rats. The water extract of propolis (PWE) completely protected β-cell destruction against STZ toxicity. The protective effect of PWE was found to be almost equal to that of nicotinamide. PWE also inhibited the interleukin-1 β (IL-1 β) generation from human leukocytes. The free radical scavenging activity together with IL-1 β and nitric oxide (NO) synthase inhibitory activities are thought to be the prime factors for the protective effect of PWE against STZ toxicity.

译文

:蜂胶是一种胶水,是由蜜蜂从植物材料中制备的,用以将其蜂巢粘贴在蜂巢壁上。它在日本作为一种健康的饮料而受到欢迎,人们相信蜂胶可以治愈炎症,心脏病甚至糖尿病和癌症。我们评估了蜂胶对大鼠链脲佐菌素(STZ)毒性的β-细胞保护作用。蜂胶(PWE)的水提取物完全保护β细胞不受STZ毒性的破坏。发现PWE的保护作用几乎等于烟酰胺的保护作用。 PWE还抑制了人类白细胞产生的白介素-1β(IL-1β)。自由基清除活性以及IL-1β和一氧化氮(NO)合酶抑制活性被认为是PWE对抗STZ毒性的保护作用的主要因素。

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