Screening programs can reduce the burden of disease, however, they can be associated with raised levels of anxiety. The risk of endometrial and ovarian cancer is increased in hereditary nonpolyposis colorectal cancer (HNPCC). There is no prospective evidence to support screening for gynecological disease in HNPCC, however, current recommendations include the use of ultrasound and endometrial biopsy. This study assesses the impact of screening for gynecological cancer on self-reported symptoms of anxiety, depression, and perceptions of health. Women from HNPCC families attending gynecological screening (n = 26) completed the Hospital Anxiety and Depression Scale and the ShortForm36v2 questionnaires prior to screening with transvaginal ultrasound, outpatient/office hysteroscopy, endometrial biopsy, and ovarian tumor marker assessment (CA125). The same questionnaires were completed at 3 and 6 months following screening (15/26). Women in HNPCC families attending for gynecological screening did not have excess symptoms of anxiety or depression at baseline in subjective comparison to other populations. The process of screening and false positive screening results had no significant impact on symptoms of anxiety and depression or perceptions of health. We conclude that within the limitations of analysis in this small study group, screening for gynecological disease in HNPCC does not appear to be associated with any psychological morbidity.

译文

筛查计划可以减轻疾病负担,但是,它们可能与焦虑水平升高有关。遗传性非息肉病性结直肠癌 (HNPCC) 发生子宫内膜癌和卵巢癌的风险增加。目前尚无前瞻性证据支持在HNPCC中筛查妇科疾病,但是,目前的建议包括使用超声和子宫内膜活检。这项研究评估了筛查妇科癌症对自我报告的焦虑,抑郁和健康观念的影响。来自HNPCC家庭的女性 (n = 26) 在接受经阴道超声,门诊/办公室宫腔镜检查,子宫内膜活检和卵巢肿瘤标志物评估 (CA125) 进行筛查之前,完成了医院焦虑和抑郁量表和ShortForm36v2问卷。在筛选后的3个月和6个月 (15/26) 完成相同的问卷。与其他人群相比,参加妇科筛查的HNPCC家庭中的女性在基线时没有过度的焦虑或抑郁症状。筛查过程和假阳性筛查结果对焦虑抑郁症状或健康感知无显著影响。我们得出的结论是,在这个小型研究组的分析局限性内,在HNPCC中筛查妇科疾病似乎与任何心理疾病无关。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录