We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female who did not respond to standard antifungal treatment. She was started on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and systemic ketoconazole was added, however, there was no response and the infiltrate increased further. She was then switched to topical and systemic voriconazole. Steady resolution of the infiltrate was noted within 2 weeks of therapy.

译文

我们报告了一名53岁,控制良好的糖尿病女性的烟曲霉性角膜炎病例,该女性对标准抗真菌治疗无反应。她开始使用局部纳他霉素滴眼液,但浸润持续进展。局部添加两性霉素b和全身性酮康唑,但无反应,浸润进一步增加。然后改用外用和全身性伏立康唑。治疗后2周内发现浸润稳定消退。

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