Thrombosed arteriovenous malformations (AVMs) are the predominant type of occult vascular malformation and do not seem to differ significantly in clinical or radiographic presentation from other types of occult vascular malformations. Thrombosed AVMs and occult vascular malformations occasionally present with symptoms secondary to subacute or occult hemorrhage that requires operation. The histopathology of thrombosed AVMs and occult vascular malformations does not seem to have prognostic significance. Five patients with histologically verified thrombosed AVMs are reported. Two patients had previous incomplete resection of histologically proven thrombosed AVMs and presented with recurrence and bleeding. Two patients presented with seizures and headaches, and one patient presented with hemiparesis and headache. All histology specimens had evidence of hemorrhage. The pathological findings of these lesions seem variable; two specimens contained a mixture of cavernous angioma and AVM. Two previously resected lesions had been defined histologically as thrombosed AVMs. Successful excision of the lesions was accomplished in four patients, and one patient had stereotactic biopsy. The magnetic resonance imaging characteristics of lesions seem to add a degree of specificity over computed tomography and angiography. We have found that the literature poorly describes the natural history and histology of these lesions. Conservative management for seizures and headaches due to thrombosed AVMs may not be warranted because of a propensity for hemorrhage and recurrence.

译文

血栓形成的动静脉畸形 (avm) 是隐匿性血管畸形的主要类型,在临床或影像学表现上似乎与其他类型的隐匿性血管畸形没有显着差异。血栓形成的avm和隐匿性血管畸形偶尔出现继发于需要手术的亚急性或隐匿性出血的症状。血栓形成的avm和隐匿性血管畸形的组织病理学似乎没有预后意义。据报道,有5例经组织学证实的血栓形成的avm患者。两名患者先前未完全切除经组织学证实的血栓形成的avm,并出现复发和出血。两名患者出现癫痫发作和头痛,一名患者出现偏瘫和头痛。所有组织学标本都有出血的证据。这些病变的病理发现似乎是可变的; 两个标本包含海绵状血管瘤和AVM的混合物。先前切除的两个病变在组织学上被定义为血栓形成的avm。四名患者成功切除了病变,一名患者进行了立体定向活检。病变的磁共振成像特征似乎比计算机断层扫描和血管造影增加了一定程度的特异性。我们发现文献对这些病变的自然史和组织学描述不佳。由于出血和复发的倾向,可能不需要对血栓形成的avm引起的癫痫发作和头痛进行保守治疗。

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