Nasal airflow, as measured by rhinomanometry, is frequently impaired in allergic rhinitis (AR). The decongestion test evaluates whether the application of an intranasal vasoconstrictor drug increases nasal airflow. The aim of this study was to verify the suitability of the use of the visual analogue scales (VAS) as a surrogate for rhinomanometry in the decongestion test assessment in adolescents with atopic rhinitis. Forty adolescents [16 males and 24 females, mean age 15 (s.d. 2) yr] with AR were studied. Nasal symptoms, VAS, rhinomanometry, and nasal decongestion test were assessed in all patients. A significant association was observed between VAS and nasal airflow after performing the decongestion test (Spearman's r is -51.7%, p < 0.001). The associated sensitivity and specificity were 84.8 (95% confidence interval, CI 68.1-94.8) and 85.7 (95% CI 42.2-97.6), respectively. The corresponding area under the receiver operating characteristic (ROC) curve of 0.83 (95% CI 0.67-0.93) indicated a good discriminating ability for the decongestion measured on the VAS scale. In conclusion, the use of VAS appears as clinically relevant, in that it allows, with a fair reliability, to perform the decongestion test in the absence of rhinomanometry.

译文

鼻气流,通过鼻压法测量,在过敏性鼻炎 (AR) 中经常受损。减充血试验评估鼻内血管收缩药物的应用是否增加鼻气流。这项研究的目的是验证在患有特应性鼻炎的青少年减充血试验评估中使用视觉模拟量表 (VAS) 作为鼻测压的替代物的适用性。研究了40名患有AR的青少年 [16名男性和24名女性,平均年龄15 (s.d. 2) 岁]。在所有患者中评估了鼻症状,VAS,鼻测压和鼻充血试验。在进行减充血试验后,观察到VAS与鼻气流之间存在显着关联 (Spearman's r为-51.7%,p <0.001)。相关的敏感性和特异性分别为84.8 (95% 置信区间,CI 68.1-94.8) 和85.7 (95% CI 42.2-97.6)。0.83的接收器工作特性 (ROC) 曲线下的相应面积 (95% CI 0.67-0.93) 表明,在VAS量表上测量的解充血具有良好的区分能力。总之,VAS的使用似乎与临床相关,因为它允许在没有鼻测压法的情况下以相当的可靠性进行减充血试验。

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