Guillain-Barré syndrome (GBS) has been rarely reported after liver transplantation and generally has good outcome. We report a liver transplant patient on FK506 (tacrolimus) who developed GBS 6 months after liver transplantation. There was no evidence of liver rejection or active infection. Despite treatment with intravenous immunoglobulin, the patient expired. GBS occurred despite downregulation of T cells by FK506, suggesting that humoral dysfunction might be the predominant mechanism of GBS in this report.

译文

肝移植后很少报道格林-巴利综合征 (GBS),并且通常具有良好的疗效。我们报告了一名FK506 (他克莫司) 肝移植患者,该患者在肝移植后6个月出现了GBS。没有肝脏排斥或活动性感染的证据。尽管使用静脉注射免疫球蛋白治疗,但患者仍过期。尽管FK506下调了T细胞,但仍发生了GBS,这表明体液功能障碍可能是本报告中GBS的主要机制。

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