Both obsessive-compulsive disorder and subclinical obsessive-compulsive (OC) symptoms seem to be associated with hyperactive error-related brain activity. The current study examined performance monitoring in subjects with subclinical OC symptoms using a new task with different levels of difficulty. Nineteen subjects with high and 18 subjects with low OC characteristics performed a random dot cinematogram (RDC) task with three levels of difficulty. The high and low OC groups did not differ in error-related negativity (ERN), correct-related negativity (CRN) and performance irrespective of task difficulty. The amplitude of the ERN decreased with increasing difficulty whereas the magnitude of CRN did not vary. ERN and CRN approached in size and topography with increasing difficulty, which suggests that errors and correct responses are processed more similarly. These results add to a growing number of studies that fail to replicate hyperactive performance monitoring in individuals with OC symptoms in task with higher difficulty or requiring learning. Together with these findings our results suggest that the relationship between OC symptoms and performance monitoring may be sensitive to type of task and task characteristics and cannot be observed in a RDC that differs from typically used tasks in difficulty and the amount of response-conflict.

译文

强迫症和亚临床强迫症 (OC) 症状似乎都与过度活跃的错误相关的大脑活动有关。当前的研究使用具有不同难度的新任务检查了具有亚临床OC症状的受试者的性能监测。19名具有高OC特征的受试者和18名具有低OC特征的受试者执行了三个难度级别的随机点电影摄影 (RDC) 任务。无论任务难度如何,高OC组和低OC组在与错误相关的负性 (ERN),与正确相关的负性 (CRN) 和性能方面都没有差异。ERN的幅度随着难度的增加而降低,而CRN的幅度没有变化。ERN和CRN的尺寸和地形越来越困难,这表明错误和正确响应的处理方式更为相似。这些结果增加了越来越多的研究,这些研究未能在难度较高或需要学习的任务中有OC症状的个体中复制过度活跃的性能监测。结合这些发现,我们的结果表明,OC症状和性能监测之间的关系可能对任务类型和任务特征敏感,并且在与困难和响应冲突量不同的RDC中无法观察到。

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