Movement disorders of various types may occur in relation to viral infections of the central nervous system. They manifest themselves as obvious signs at clinical onset or during the acute phase of an encephalitis (myoclonus, tremor, or parkinsonism), or appear as later sequelae decades after the illness. We describe here a man who developed an unusual movement disorder after a probable viral encephalitis in his childhood. This consisted of a tremor (3-4Hz frequency and 100-150ms duration) of the neck, left shoulder and arm, which persisted unchanged during the ensuing years. The patient regarded this abnormal movement as annoying, but otherwise it did not impair his lifestyle. He subsequently developed the clinical picture of parkinsonism many decades after the onset of tremor, and we speculate that both tremor and parkinsonism can be considered sequelae of encephalitis, but each with a different time-course. The left-sided jerky tremor was an immediate sequela in the childhood; whereas, the rigid-akinetic parkinsonian picture represented a later sequela of the infection in old age. The injured site responsible for both the segmental tremor and the parkinsonism presumably involved the brainstem.

译文

各种类型的运动障碍可能与中枢神经系统的病毒感染有关。它们在临床发作时或脑炎急性期 (肌阵挛,震颤或帕金森氏症) 表现为明显的体征,或在疾病后数十年出现后遗症。我们在这里描述了一个在童年时期可能发生病毒性脑炎后出现异常运动障碍的人。这包括颈部,左肩和手臂的震颤 (3-4hz频率和100-150ms持续时间),在随后的几年中一直保持不变。患者认为这种异常运动令人讨厌,但并没有损害他的生活方式。随后,他在震颤发作数十年后发展了帕金森氏症的临床表现,我们推测震颤和帕金森氏症都可以被认为是脑炎的后遗症,但每个都有不同的时程。左侧的生涩震颤是童年时期的直接后遗症; 然而,僵硬的运动性帕金森病的照片代表了老年感染的后遗症。引起节段性震颤和帕金森病的受伤部位可能涉及脑干。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录