Malignant transformation of synovial chondromatosis into chondrosarcoma is unusual. Thirteen cases and one series have been reported; only four of them developed in the hip. The overall survival is about 50%, possibly because of the difficulty of arriving at a correct early diagnosis (radiographically and histologically) and subsequent adequate surgical therapy. We report two patients (ages 30 and 50 years) in whom synovial chondrosarcoma developed in previously excised synovial chondromatosis of the hip. The diagnosis was made with modern imaging techniques (computed tomography and magnetic resonance imaging) and verified by open biopsy. The early recognition allowed a wide limb-saving resection; both patients are disease free 3 and 2 years after surgery.

译文

滑膜软骨瘤病向软骨肉瘤的恶性转化是不常见的。已报告了13例和一系列; 其中只有四例在臀部发育。总生存率约为50%,可能是因为难以获得正确的早期诊断 (放射学和组织学) 以及随后的适当手术治疗。我们报告了两名患者 (年龄分别为30岁和50岁),其中滑膜软骨肉瘤是在先前切除的髋关节滑膜软骨瘤中发展的。诊断是通过现代成像技术 (计算机断层扫描和磁共振成像) 进行的,并通过开放活检进行了验证。早期识别允许广泛的肢体切除; 两名患者在手术后3年和2年均无病。

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