This study evaluates long-term ( > 10 years since surgery) right ventricular (RV) systolic function in patients who had previously undergone intraatrial baffle surgery for transposition of the great arteries. Studies suggest these patients are clinically stable and lead satisfactory lifestyles, but long-term ventricular performance is not known. Radionuclide angiocardiography was used to estimate RV ejection fraction in 58 patients a mean of 14 years after the Mustard operation. Repeat studies were performed in 32 patients. The absolute RV ejection fraction of 0.53 +/- 0.10 in our patients did not differ from normal values. Nine patients had a value < 0.42, placing them > 2 SDs below normal. Repeat RV ejection fraction decreased from 0.54 +/- 0.11 to 0.51 +/- 0.11 (p < 0.1) in 32 patients, and > 0.10 in 6. Thus, RV ejection fraction was abnormal in 9 of 58 patients (16%) evaluated > 10 years after a Mustard operation. Repeat studies demonstrate worsening in at least 6 of 32 patients (19%). These postoperative Mustard patients require continued evaluation, even in the absence of overt symptomatology.

译文

这项研究评估了先前接受过大动脉转位的房内挡板手术的患者的长期 (自手术以来> 10年) 右心室 (RV) 收缩功能。研究表明,这些患者临床稳定,生活方式令人满意,但长期心室性能尚不清楚。放射性核素心血管造影用于估计芥末手术后平均14年的58例患者的RV射血分数。对32例患者进行了重复研究。在我们的患者中,0.53 +/- 0.10的RV绝对射血分数与正常值没有差异。9名患者的值 <0.42,使他们> 2 SDs低于正常。32例患者的RV射血分数从0.54 +/- 0.11降至0.51 +/- 0.11 (p <0.1),6例患者> 0.10。因此,在芥末手术后10年以上评估的58名患者 (16% 名) 中有9名RV射血分数异常。重复研究表明32例患者中至少有6例 (19% 例) 恶化。即使没有明显的症状,这些术后芥末患者也需要继续评估。

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