The reproducibility of nasal spirometry was assessed in ten subjects at two visits. Topical nasal decongestion was applied to minimise mucosal variation. Eleven parameters of flow volume were measured. Data analysis using Spearman's rank correlation coefficients revealed peak inspiratory flow rate (PIFR) followed by forced expiratory volume in first one second (FEV1) to be the most reproducible measures, yielding significance values of < 0.05. For all other spirometric parameters significance was not reached. Analysis revealed that using a naso-pulmonary index (a ratio of nasal to pulmonary flow) was detrimental to reproducibility. We conclude that future nasal spirometric studies should use PIFR and FEV1 as their derived variables of flow-volume loops in the assessment of nasal patency, and the naso-pulmonary index is of no value.

译文

在两次访问中评估了十名受试者的鼻肺活量测定法的可重复性。应用局部鼻充血以最大程度地减少粘膜变异。测量了11个流量参数。使用Spearman秩相关系数进行的数据分析显示,峰值吸气流速 (PIFR) 和第一秒的用力呼气量 (FEV1) 是最可重复的量度,产生的显著性值 <0.05。对于所有其他肺活量参数,未达到显着性。分析表明,使用鼻肺指数 (鼻与肺流量的比率) 不利于重现性。我们得出的结论是,在评估鼻腔通畅性时,未来的鼻肺活量研究应使用PIFR和FEV1作为其流量循环的衍生变量,而鼻肺指数没有价值。

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