OBJECTIVES:This study investigated whether the measurement of mitral annulus displacement by the tissue-tracking method with Doppler-tissue images can provide more accurate information on the severity of heart failure compared to conventional methods, such as left ventricular ejection fraction (LVEF). BACKGROUND:Impaired left ventricular function is an important predictor of poor prognosis. Although LVEF has been used to assess left ventricular function, such indicators do not necessarily correlate well to clinical variables such as New York Heart Association (NYHA) functional class or plasma brain natriuretic peptide (BNP) concentration. METHODS:In 90 subjects with or without various heart diseases, mitral annulus displacement was measured by the tissue-tracking method with Doppler-tissue images and the correlations evaluated with NYHA functional class, plasma BNP concentration, left ventricular mass index and Tei index. RESULTS:Mitral annulus displacement by the tissue-tracking method with Doppler-tissue images was well correlated with NYHA functional class and plasma BNP concentration. LVEF was also correlated with these clinical variables, but significantly more weakly. Furthermore, mitral annulus displacement by the tissue-tracking method with Doppler-tissue images was correlated with left ventricular mass index and Tei index, which indicate left ventricular systolic and diastolic function. CONCLUSIONS:The present study suggests that mitral annulus displacement measured by our technique is a useful and reliable method for assessing the severity of heart failure.

译文

目的:本研究调查了使用多普勒组织图像的组织追踪方法测量二尖瓣环移位是否可以提供比常规方法(如左心室射血分数(LVEF))更准确的心力衰竭严重程度信息。
背景:左心室功能受损是预后不良的重要预测指标。尽管LVEF已用于评估左心室功能,但此类指标不一定与临床变量(例如纽约心脏协会(NYHA)功能类别或血浆脑钠肽(BNP)浓度)具有良好的相关性。
方法:对90例患有或未患有多种心脏病的受试者,采用多普勒组织图像组织追踪法测量二尖瓣环移位,并通过NYHA功能类别,血浆BNP浓度,左心室质量指数和Tei指数评估相关性。
结果:采用多普勒组织图像的组织追踪法检测二尖瓣环移位与NYHA功能类别和血浆BNP浓度密切相关。 LVEF也与这些临床变量相关,但明显较弱。此外,采用多普勒组织图像的组织追踪法进行的二尖瓣环移位与左心室质量指数和Tei指数相关,表明左心室收缩和舒张功能。
结论:本研究表明,用我们的技术测量的二尖瓣环移位是评估心力衰竭严重程度的一种有用且可靠的方法。

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