Carbon nanotubes (CNT) possess excellent mechanical properties to play the role as reinforcement for imparting strength and toughness to brittle hydroxyapatite (HA) bioceramic coating. However, lack of processing technique to uniformly distribute multiwalled CNTs in HA coating and limited studies and sparse knowledge evincing toxicity of CNTs has kept researchers in dispute for long. In the current work, we have addressed these issues by (i) successfully distributing multiwalled CNT reinforcement in HA coating using plasma spraying to improve the fracture toughness (by 56%) and enhance crystallinity (by 27%), and (ii) culturing human osteoblast hFOB 1.19 cells onto CNT reinforced HA coating to elicit its biocompatibility with living cells. Unrestricted growth of human osteoblast hFOB 1.19 cells has been observed near CNT regions claiming assistance by CNT surfaces to promote cell growth and proliferation.

译文

:碳纳米管(CNT)具有出色的机械性能,可充当增强剂,为脆性羟基磷灰石(HA)生物陶瓷涂层赋予强度和韧性。然而,缺乏在HA涂层中均匀分布多壁CNT的加工技术,有限的研究以及有关CNTs毒性的稀疏知识一直困扰着研究人员。在当前的工作中,我们已通过以下方法解决了这些问题:(i)使用等离子喷涂成功地在HA涂层中分配多壁CNT增强材料,以提高断裂韧性(提高56%)和增强结晶度(提高27%),以及(ii)培养人将成骨细胞hFOB 1.19细胞涂在CNT增强的HA涂层上,以引发其与活细胞的生物相容性。在CNT区域附近观察到人类成骨细胞hFOB 1.19细胞的生长不受限制,声称其受CNT表面的辅助来促进细胞生长和增殖。

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