BACKGROUND:The assessment of mood and anxiety disorders secondary to cancer by using easy-to-administer instruments has been the object of recent research. METHODS:The aim of this study was to examine the accuracy of the short screening tool developed by the National Comprehensive Cancer Network Clinical Practice Guidelines for Distress Management, (0-10 point-scale Distress Thermometer) (DT) in detecting affective syndrome disorders in Italian cancer patients. The sample consisted of 109 cancer outpatients who were administered the ICD-10 psychiatric interview (CIDI), the DT and the Hospital Anxiety Depression Scale (HADS). RESULTS:Forty-four patients (40.4%) met the criteria for an ICD-10 diagnosis of affective syndromes. The DT was significantly associated with HADS-Total score (r=0.66, p=0.001). A cut-off > or = 4 on the DT showed a sensitivity of 79.5% and a specificity of 75.4% (positive predictive value--PPV = 68.6%; negative predictive value--NPV = 84.5%). The cut-off score > or = 10 on the HADS was associated with a sensitivity of 86% and a specificity of 81.5% (PPV = 76%; NPV = 89.9%). A cut-off score > or = 5 on DT and > or = 15 on HADS maximized sensitivity (78.6% and 85%, respectively) and specificity (83.1% and 96%, respectively) for patients with more severe affective syndromes (major depression, persistent depressive disorders). CONCLUSIONS:The results suggest that simple instruments can be used as feasible tools in the screening of mood and anxiety disorders among cancer patients.

译文

背景:使用易于管理的仪器评估癌症继发的情绪和焦虑症已成为近期研究的目标。
方法:本研究的目的是检验由《国家综合癌症网络遇险管理临床实践指南》(0-10点规模遇险温度计)(DT)开发的短筛查工具在检测情感综合征中的准确性。意大利癌症患者。该样本包括109位接受过ICD-10精神病学访谈(CIDI),DT和医院焦虑抑郁量表(HADS)的癌症门诊患者。
结果:44名患者(40.4%)符合ICD-10诊断情感综合征的标准。 DT与HADS总分显着相关(r = 0.66,p = 0.001)。 DT的临界值>或= 4显示灵敏度为79.5%,特异性为75.4%(阳性预测值-PPV = 68.6%;阴性预测值--NPV = 84.5%)。 HADS的截止评分>或= 10与敏感性86%和特异性81.5%相关(PPV = 76%; NPV = 89.9%)。 DT的临界值>或= 5,HADS的> 15或15以上,对于患有更严重的情感综合征(重度抑郁)的患者,其敏感性最高(分别为78.6%和85%)和特异性(分别为83.1%和96%) ,持续性抑郁症)。
结论:结果表明,简单的仪器可用作筛查癌症患者情绪和焦虑障碍的可行工具。

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