Solid and papillary epithelial neoplasm (SPENP) of the pancreas is a rare pancreatic tumour of low malignant potential, that is seen mostly in young females. The aetiology and pathogenesis is unclear but it is considered to be arising from primordial pancreatic cells. We report two cases of SPENP who had palpable abdominal lumps and were diagnosed on histopathology. In the first case, the tumour was unresectable and patient died within one year. In the second case, at laprotomy the patient had perineurial as well as capsular infiltration but after wide resection of the growth, patient has been doing well for the past 6 months. Since SPENP is a low grade malignant neoplasm, it should be treated aggressively with complete resection and metastatectomy. Prognosis after adequate surgery is good. A clinicopathological study and brief review of literature is presented.

译文

:胰腺的乳头状和乳头状上皮性肿瘤(SPENP)是一种罕见的低恶性潜能的胰腺肿瘤,多见于年轻女性。病因和发病机制尚不清楚,但被认为起源于原始胰腺细胞。我们报告了2例SPENP患者,他们有明显的腹部肿块,并经组织病理学确诊。在第一种情况下,肿瘤无法切除,患者在一年内死亡。在第二种情况下,在腹膜切开术中,患者有尿道周和囊膜浸润,但是在广泛切除生长后,患者在过去的6个月中一直表现良好。由于SPENP是低度恶性肿瘤,因此应通过彻底切除和转移切除术积极治疗。适当手术后预后良好。提出了临床病理学研究和文献简要回顾。

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