Febrile seizures are the most common seizures of childhood. A family history of febrile seizures is common, and the disorder is genetically heterogenous. While guidelines are available for management of simple febrile seizures, the management of complex febrile seizures is individualised. After a febrile seizure, it is important to rule out CNS infection and the decision to perform a lumbar puncture should be based on the clinical condition of the child. Neuroimaging and EEG are not required immediately in workup for simple or complex febrile seizures. Recurrence of febrile seizures may be managed at home by the parents with benzodiazepines. If the recurrences are multiple or prolonged and parents are unable to give home treatment, intermittent benzodiazepine prophylaxis may be given. Continuous antiepileptic prophylaxis may be given only to the children where intermittent prophylaxis has failed. Febrile seizures are also associated with increased risk of epilepsy, but this cannot be prevented by any form of treatment. There is also an increased risk of mesial temporal sclerosis, but whether this is an effect or cause of febrile seizures is as yet unclear. There is no increase in neurological handicaps or mortality following febrile seizures.

译文

:高热惊厥是儿童最常见的惊厥。高热惊厥的家族病史很普遍,该疾病在遗传上是异质的。虽然有指导可用于管理简单的高热惊厥,但是对复杂的高热惊厥的治疗是个体化的。高热惊厥后,重要的是要排除CNS感染,应根据儿童的临床情况决定是否进行腰穿。对于简单或复杂的高热惊厥,无需立即进行神经影像检查和脑电图检查。苯二氮卓类药物的父母可在家中控制高热惊厥的复发。如果复发是多次的或延长的,并且父母无法给予家庭治疗,则可以间歇性地预防苯二氮卓类药物。持续的抗癫痫预防只能用于间歇性预防失败的儿童。高热惊厥也与癫痫风险增加有关,但这不能通过任何形式的治疗来预防。中间颞叶硬化的风险也增加了,但是,这是高热惊厥的影响还是原因尚不清楚。高热惊厥后神经障碍或死亡率没有增加。

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