The purpose of this investigation was to evaluate the effectiveness of a behavioral treatment package to reduce chronic sleep problems in children with Angelman Syndrome. Participants were five children, 2-11 years-of-age. Parents maintained sleep diaries to record sleep and disruptive nighttime behaviors. Actigraphy was added to provide independent evaluations of sleep-wake activity. The treatment package targeted the sleep environment, the sleep-wake schedule, and parent-child interactions during sleep times. Treatment was introduced sequentially, across families, and evaluated in an interrupted time series, multiple baseline design. Data show that prior to treatment, baseline rates of nighttime disruptive behavior were stable or increasing and none of the participants were falling to sleep independently. With the introduction of treatment, all participants quickly learned to initiate sleep independently. Gradual reductions were reported in disruptive behaviors and these improvements were sustained over time. Results were replicated with two participants when treatment was withdrawn and reinstated. Changes in disruptive bedtime behaviors and in sleep onset were found to be statistically significant. Parents indicated high satisfaction with the treatment. A behavioral treatment package was found to be effective with five children with long histories of significant sleep-related behavior problems. These results suggest that behavioral treatment may be a reasonable way to address sleep problems in some children with Angelman Syndrome.

译文

:这项研究的目的是评估行为治疗方案以减少Angelman综合征患儿的慢性睡眠问题的有效性。参加者为5个年龄在2-11岁之间的儿童。父母保留睡眠日记以记录睡眠和夜间行为。增加了书法,以提供对睡眠觉醒活动的独立评估。该治疗方案针对睡眠环境,睡眠唤醒计划以及睡眠期间的亲子互动。在各个家庭中按顺序引入治疗方法,并在中断的时间序列和多个基线设计中进行评估。数据显示,在治疗之前,夜间破坏行为的基线率稳定或上升,并且没有参与者独立入睡。随着治疗的引入,所有参与者很快学会了独立开始睡眠。据报道,破坏性行为逐渐减少,并且随着时间的推移,这些改善持续存在。退出治疗并恢复治疗时,两名参与者重复了结果。发现破坏性的就寝时间行为和睡眠发作的变化在统计学上是显着的。父母对治疗表示高度满意。发现行为治疗一揽子方法对五个有悠久的重大睡眠相关行为问题病史的儿童有效。这些结果表明,行为治疗可能是解决某些Angelman综合征儿童睡眠问题的合理方法。

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