Understanding the impact of peripheral artery disease (PAD) requires broad evaluation of how functional limitations of PAD affect patients' perceptions of health-related quality of life (HRQL). The objective of this study was to describe the development, testing, and psychometric properties of the PAD Quality of Life Questionnaire (PADQOL). The PADQOL was developed in three steps: (1) interviews of symptomatic PAD patients provided content of the initial questionnaire; (2) co-administration with the SF-36 (a 36-item short-form health survey), Walking Impairment Questionnaire, and Profile of Mood States examined construct validity; and (3) a three-phased factor analysis identified factors and shortened the questionnaire. Data analyses from 297 symptomatic PAD patients resulted in a 38-item questionnaire of five factors: Social relationships and interactions, Self-concept and feelings, Symptoms and limitations in physical functioning, Fear and uncertainty, and Positive adaptation (α = 0.92-0.73) and items related to sexual function, intimate relationships and employment. Between-instrument correlations established construct validity. In conclusion, PADQOL is a validated measure to assess the disease-specific physical, psychosocial and emotional effects of PAD for research and practice.

译文

:了解外周动脉疾病(PAD)的影响需要对PAD的功能局限性如何影响患者对健康相关生活质量(HRQL)的看法进行广泛评估。这项研究的目的是描述PAD生活质量问卷(PADQOL)的发展,测试和心理计量学特性。 PADQOL的开发分为三个步骤:(1)有症状的PAD患者的访谈提供了初始问卷的内容; (2)与SF-36(36个项目的简短健康调查),步行障碍问卷和情绪状态概况共同管理,检验构建体的有效性; (3)通过三阶段因素分析确定因素并缩短问卷。从297名有症状的PAD患者中进行的数据分析得出了一个包含38个项目的问卷,涉及五个因素:社会关系和互动,自我概念和感觉,身体功能的症状和局限,恐惧和不确定性以及积极适应(α= 0.92-0.73)以及与性功能,亲密关系和就业有关的项目。仪器之间的相关性建立了结构效度。总之,PADQOL是一种经过验证的评估方法,可评估PAD在研究和实践中特定疾病的身体,心理和情感影响。

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