Hydrogels have gained wide usage in a range of biomedical applications because of their biocompatibility and the ability to finely tune their properties, including viscoelasticity. The use of hydrogels on the microscale is increasingly important for the development of drug delivery techniques and cellular microenvironments, though the ability to accurately characterize their micromechanical properties is limited. Here we demonstrate the use of microelectromechanical systems (MEMS) resonant sensors to estimate the properties of poly(ethylene glycol) diacrylate (PEGDA) microstructures over a range of concentrations. These microstructures are integrated on the sensors by deposition using electrohydrodynamic jet printing. Estimated properties agree well with independent measurements made using indentation with atomic force microscopy.

译文

:水凝胶具有生物相容性和微调其特性(包括粘弹性)的能力,因此在生物医学领域得到了广泛的应用。尽管精确表征其微机械性能的能力受到限制,但是在微尺度上使用水凝胶对于药物输送技术和细胞微环境的发展越来越重要。在这里,我们演示了使用微机电系统(MEMS)共振传感器来估算一系列浓度范围内的聚乙二醇二丙烯酸酯(PEGDA)微结构的性能。这些微结构通过使用电动流体喷射印刷沉积而集成在传感器上。估计的性能与使用原子力显微镜压痕法进行的独立测量非常吻合。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录