Many standard textbooks of physiology have a diagram that shows the transporting elements that lead to the secretion of HCl by the parietal cell. The transporters are neatly aligned, and students see an elegant mechanism that neatly balances the ions to maintain electroneutrality. They little realize the time and effort required to tease out each of those steps bit by bit. This essay uses three papers by Horace Davenport to highlight the experimental evidence for a crucial step in that process: the generation of H(+) and HCO(3)(-) through the agency of carbonic anhydrase. All three papers form part of the classic papers available through the American Physiological Society Legacy Project.

译文

:许多生理学标准教科书都有一张图表,显示了导致顶细胞分泌HCl的转运元素。转运蛋白排列整齐,学生们看到了一种优雅的机制,它可以平衡离子以保持电子中性。他们几乎没有一点一点地花时间来梳理每个步骤所需要的时间和精力。本文使用Horace Davenport的三篇论文来强调该过程中关键步骤的实验证据:通过碳酸酐酶的作用生成H()和HCO(3)(-)。所有这三篇论文都是可通过美国生理学会旧版计划获得的经典论文的一部分。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录