PURPOSE:The aim of this article is to propose a quantitative methodology for determining a criterion to discriminate the nonsurgical nuclear cataract from the surgical one taking into account objective measures of intraocular scattering in patients with good visual acuity (>0.6). METHODS:Two groups of subjects were taken into account: a control group and a group with nuclear cataracts. At a first stage, eyes belonging to the cataract group were classified into "nonsurgical" and "surgical" cataracts by ophthalmologists at their clinical settings. At a second stage a double-pass instrument was also used to determine the objective scatter index (OSI) at the laboratory. Receiver operating characteristic (ROC) curves were used to analyze OSI values to determine a value able to separate between nonsurgical and surgical cataracts. RESULTS:We obtained statistically significant differences among the control and both nuclear cataract groups (p < 0.05). ROC curves determined an OSI criterion level (of 2.1) to suggest surgery in nuclear cataracts with an area under curve of 0.83, i.e. with 80% of sensitivity and 80% of specificity. CONCLUSIONS:ROC analysis allows separating both groups of nuclear cataract, and we determined a value of OSI in nuclear cataract quantification for surgery.

译文

目的:本文的目的是提出一种定量方法,用于确定将非手术性核性白内障与手术性白内障区别开来的标准,同时考虑到对具有良好视力(> 0.6)的患者眼内散射的客观测量。
方法:考虑两组受试者:对照组和患有核性白内障的组。在第一阶段,眼科医生在其临床环境中将属于白内障组的眼睛分为“非手术性”和“手术性”白内障。在第二阶段,还使用双通道仪器确定实验室的客观散射指数(OSI)。接收者操作特征(ROC)曲线用于分析OSI值,以确定能够在非手术性白内障和手术性白内障之间进行区分的值。
结果:我们在对照组和两个核性白内障组之间均获得了统计学上的显着差异(p <0.05)。 ROC曲线确定了OSI标准水平(为2.1),建议在核白内障下进行手术,其曲线下面积为0.83,即敏感性为80%,特异性为80%。
结论:ROC分析可将两组白内障分开,我们确定OSI在手术白内障定量中的价值。

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