Clopidogrel is a potent inhibitor of platelet aggregation and has been used as an alternative, or as an adjunct to aspirin in reducing the risk of thrombosis. A 34-year-old uremic type 1 male diabetic patient who underwent simultaneous kidney-pancreas transplantation was given clopidogrel as he was allergic to aspirin. He developed polyarthralgia one week later, followed in a few days by symmetrical migratory polyarthritis, which resolved completely on withdrawing the drug. The implications to clinical management in a transplant setting are discussed.

译文

:Clopidogrel是一种有效的血小板聚集抑制剂,已被用作替代品,或作为阿司匹林的辅助剂以降低血栓形成的风险。一名同时接受肾胰腺移植的34岁尿毒症1型男性糖尿病患者因对阿司匹林过敏而接受了氯吡格雷治疗。一周后,他患上了多发性关节痛,几天后又出现了对称性迁徙性多发性关节炎,这种症状在撤药后完全消失了。讨论了对移植环境中临床管理的影响。

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