Low-frequency respiratory impedance (Zrs) was measured by applying a forcing signal, between 0.5 and 21 Hz at a transrespiratory pressure of 20 cm H(2)O, in a cross-sectional study of 37 normal infants. A model containing an airway resistance (Raw) and inertance (Iaw) and a tissue damping (G) and elastance (H) was fitted to the individual Zrs. Forced expiratory volume in 0.5 second (FEV(0.5)) was determined using the raised volume rapid thoracic compression technique. Multivariate regression analysis was used to analyze the relationships between the lung function parameters and length. Both airway and tissue parameters showed a decreasing quadratic relationship with increasing length. FEV(0.5) showed an increasing cubic relationship with length. A family history of asthma was found to have a negative effect on Raw, H, and FEV(0.5).

译文

:在37例正常婴儿的横断面研究中,通过在20 cm H(2)O的跨呼吸压力下施加0.5至21 Hz之间的强迫信号来测量低频呼吸阻抗(Zrs)。将包含气道阻力(Raw)和惯性(Iaw)以及组织阻尼(G)和弹性(H)的模型拟合到各个Zrs。使用增加体积的快速胸廓压缩技术确定0.5秒内的呼气量(FEV(0.5))。多元回归分析用于分析肺功能参数和长度之间的关系。气道和组织参数均显示出随着长度增加而减小的二次关系。 FEV(0.5)随长度增加呈立方关系。发现哮喘家族史对Raw,H和FEV有负面影响(0.5)。

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