Bats are reservoirs of numerous zoonotic viruses. The Picornaviridae family comprises important pathogens which may infect both humans and animals. In this study, a bat-related picornavirus was detected from Algerian Minioptreus schreibersii bats for the first time in the country. Molecular analyses revealed the new virus originates to the Mischivirus genus. In the operational use of the acquired sequence and all available data regarding bat picornaviruses, we performed a co-evolutionary analysis of mischiviruses and their hosts, to authentically reveal evolutionary patterns within this genus. Based on this analysis, we enlarged the dataset, and examined the co-evolutionary history of all bat-related picornaviruses including their hosts, to effectively compile all possible species jumping events during their evolution. Furthermore, we explored the phylogeny association with geographical location, host-genus and host-species in both data sets.

译文

蝙蝠是众多人畜共患病毒的储存库。小核糖核酸病毒科包括可能感染人类和动物的重要病原体。在这项研究中,该国首次从阿尔及利亚小optreus schreibersii蝙蝠中检测到与蝙蝠相关的小核糖核酸病毒。分子分析显示,新病毒起源于Mischi病毒属。在对获得的序列和有关蝙蝠小核糖核酸病毒的所有可用数据的操作使用中,我们对mischivirus及其宿主进行了共同进化分析,以真实地揭示该属中的进化模式。基于此分析,我们扩大了数据集,并检查了所有与蝙蝠相关的小核糖核酸病毒 (包括其宿主) 的共同进化历史,以有效地汇编其进化过程中所有可能的物种跳跃事件。此外,我们在两个数据集中都探索了系统发育与地理位置,寄主属和寄主物种的关联。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录