Cannabis as a medicine was used before the Christian era in Asia, mainly in India. The introduction of cannabis in the Western medicine occurred in the midst of the 19th century, reaching the climax in the last decade of that century, with the availability and usage of cannabis extracts or tinctures. In the first decades of the 20th century, the Western medical use of cannabis significantly decreased largely due to difficulties to obtain consistent results from batches of plant material of different potencies. The identification of the chemical structure of cannabis components and the possibility of obtaining its pure constituents were related to a significant increase in scientific interest in such plant, since 1965. This interest was renewed in the 1990's with the description of cannabinoid receptors and the identification of an endogenous cannabinoid system in the brain. A new and more consistent cycle of the use of cannabis derivatives as medication begins, since treatment effectiveness and safety started to be scientifically proven.

译文

大麻作为药物在基督教时代之前在亚洲使用,主要在印度。西药中大麻的引入发生在19世纪之中,随着大麻提取物或酊剂的供应和使用,在那个世纪的最后十年达到了高潮。在20世纪的头几十年中,由于难以从不同功效的植物材料批次中获得一致的结果,西方医学对大麻的使用显着减少。1965年,鉴定大麻成分的化学结构以及获得其纯成分的可能性与对这种植物的科学兴趣的显着提高有关。20世纪90年代对大麻素受体的描述和对大脑中内源性大麻素系统的鉴定,重新激发了这种兴趣。由于治疗有效性和安全性开始得到科学证明,因此开始了使用大麻衍生物作为药物的新的,更一致的周期。

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