The aim of this study is to describe the prevalence of gastroesophageal reflux disease (GERD) in infants under 3 months old with a history of cyanotic episodes, who were examined at the emergency room of a university hospital. This descriptive study reviews reports of esophageal pH monitoring from a pediatric gastroenterology service over a period of 5 years. The following data were collected: age, sex, pediatric as well as other specialists' evaluations, and the esophageal pH monitoring reports. This study included 67 infants with a history of cyanotic episodes, with no primary cause determined by pediatrician and pediatric specialists' evaluations, who underwent esophageal pH monitoring. The infants were 6-90 days old, 41 (61.2%) of them male. Fifty infants (74.6%) had at least one esophageal pH monitoring parameter above the normal limit. ZMD index was abnormal in 32 cases (48%) and reflux index was abnormal in 31 cases (46%). When other common causes of cyanosis have been ruled out, a significant proportion of infants presenting cyanosis have abnormal pH study, suggesting the role of GERD in cyanosis. The authors highlight that reflux index is not enough to conclude whether a pH study is normal or not. The ZMD index and the presence of episodes longer than 20 minutes are also important parameters for GERD diagnosis.

译文

这项研究的目的是描述在大学医院急诊室检查的3个月以下有发绀发作史的婴儿中胃食管反流病 (GERD) 的患病率。这项描述性研究回顾了儿科胃肠病服务机构在5年内进行的食管pH监测报告。收集了以下数据: 年龄,性别,儿科以及其他专家的评估以及食管pH监测报告。这项研究包括67名有发绀发作史的婴儿,这些婴儿没有由儿科医生和儿科专家评估确定的主要原因,他们接受了食道pH监测。婴儿为6-90天,其中男性41 (61.2%)。50名婴儿 (74.6%) 至少有一个食管pH监测参数高于正常限值。ZMD指数异常32例 (48%),反流指数异常31例 (46%)。如果排除了其他常见的发绀原因,则有相当一部分出现发绀的婴儿进行了异常pH研究,这表明GERD在发绀中的作用。作者强调,反流指数不足以得出pH研究是否正常的结论。ZMD指数和发作时间超过20分钟也是GERD诊断的重要参数。

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