Cefditoren pivoxil is an oral antimicrobial used increasingly in pediatric bacterial infections. We report a case of rash and arthralgia following administration of cefditoren pivoxil for lower respiratory tract infection in a four-year-old female child. On discontinuation of the antibiotic, the child recovered full function of the knee joint within seven days. The causality of the event assessed as per the WHO-UMC system for standardized case causality assessment criteria can be considered as 'probable'. Analyzed by the Naranjo's ADR probability scale, the score was 7, which also makes it a 'probable' event.

译文

头孢托仑pivoxil是一种口服抗菌剂,越来越多地用于小儿细菌感染。我们报告了一名四岁女童使用头孢托仑pivoxil治疗下呼吸道感染后出现皮疹和关节痛的情况。停用抗生素后,孩子在7天内恢复了膝关节的全部功能。根据WHO-UMC标准化案例因果关系评估标准系统评估的事件因果关系可被视为 “可能”。通过Naranjo的ADR概率量表分析,得分为7,这也使其成为 “可能” 事件。

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