Cutaneous manifestations of petechiae, purpura, and ecchymosis can lead the physician to discover an underlying platelet abnormality. Autoimmune idiopathic thrombocytopenic purpura (AITP) is a diagnosis of exclusion, mediated by a destructive IgG antibody response to the platelets' membrane components. In addition to showing evidence of cutaneous and mucosal bleeding (ie, epistaxis, hematuria), patients with AITP are at an increased risk for systemic lupus erythematosus (SLE). Therefore, it is suggested that patients with AITP be closely monitored for SLE.

译文

瘀点,紫癜和瘀斑的皮肤表现可导致医生发现潜在的血小板异常。自身免疫性特发性血小板减少性紫癜 (AITP) 是一种排除的诊断,由对血小板膜成分的破坏性IgG抗体反应介导。除了显示皮肤和粘膜出血 (即鼻出血,血尿) 的证据外,AITP患者患系统性红斑狼疮 (SLE) 的风险增加。因此,建议密切监测AITP患者的SLE。

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