A 66-year-old man, admitted to the hospital for prostatic carcinoma, presented with a nodular lesion located on the presternal region and a small nodule (0.5 cm in diameter) simulating a scalp sebaceous cyst located on the scalp. Moreover, an irregular darkbrown lesion was observed on the left side of the abdomen, and a brownish macula was also present on the presternal region. Histologic examination of the two nodular lesions revealed cutaneous metastases from prostatic carcinoma. The pigmented lesion, localized on the abdomen, proved to be a superficial spreading melanoma with a maximal depth of 1.36 mm. Histologic examination of the brownish lesion on the presternal region revealed nevus cell nests within the epidermis and in the dermis. We discuss the propensity of developing a secondary cancer in a patient with a primary malignancy.

译文

一名66岁的男子因前列腺癌入院,表现为位于胸骨前区的结节状病变和位于头皮上的小结节 (直径0.5厘米),模拟头皮皮脂腺囊肿。此外,在腹部左侧观察到不规则的深褐色病变,胸骨前区域也出现褐色黄斑。对两个结节性病变的组织学检查显示前列腺癌的皮肤转移。位于腹部的色素性病变被证明是表面扩散的黑色素瘤,最大深度为1.36毫米。对胸骨前区域的褐色病变进行组织学检查,发现表皮和真皮内有痣细胞巢。我们讨论了原发性恶性肿瘤患者发生继发性癌症的倾向。

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